Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 3/20 | 0.52 |
| ▸ | SFRP1 | Q8N474 | 6/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | WNT3 | P56703 | 2/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31615446 | 1.00 | MEN1 (0.55) | MEN1KMT2ABRD4SFRP1CCR8 | |
| SCHEMBL4122520 | 1.00 | MEN1 (0.55) | MEN1KMT2ABRD4SFRP1CCR8 | |
| SCHEMBL18230360 | 0.94 | MEN1 (0.58) | MEN1KMT2ABRD4SFRP1CCR8 | |
| SCHEMBL2107778 | 0.94 | MEN1 (0.60) | MEN1KMT2ABRD4SFRP1CCR8 | |
| SCHEMBL31234802 | 0.94 | MEN1 (0.60) | MEN1KMT2ABRD4SFRP1CCR8 | |
| SCHEMBL4101640 | 0.85 | MEN1 (0.62) | MEN1KMT2ADRD2ADRA1DADRA1A | |
| SCHEMBL4101645 | 0.85 | MEN1 (0.62) | MEN1KMT2ADRD2ADRA1DADRA1A | |
| SCHEMBL30099305 | 0.83 | ALDH1A1 (0.53) | BRD4SFRP1CCR8USP30ALDH1A1 | |
| SCHEMBL13696749 | 0.83 | ALDH1A1 (0.53) | BRD4SFRP1CCR8USP30ALDH1A1 | |
| SCHEMBL15932401 | 0.83 | BRD4 (0.55) | BRD4SFRP1CCR8USP30MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494670-A1 | MEDICINE FOR TREATING CANCER | Kowa Co., Ltd. (JP) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003086397-A1 | MEDICINE FOR TREATING CANCER | KOWA CO., LTD. (JP) | 2003-10-23 | — | — | WO | disclosed |