Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.38 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TEC | P42680 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169530 | 0.91 | HCRTR1 (0.39) | HCRTR1HCRTR2KDM4EHSD17B10ABCB1 | |
| SCHEMBL6166854 | 0.86 | HCRTR1 (0.36) | HCRTR1HCRTR2PTGDR2PREPABCB1 | |
| Ethylene SCHEMBL4120382 | 0.83 | PDE4D (0.43) | HCRTR1HCRTR2WNK1HDAC1PDE4D | |
| SCHEMBL4122248 | 0.83 | PDE4D (0.45) | HCRTR1HCRTR2WNK1HDAC1PDE4D | |
| SCHEMBL4115040 | 0.74 | RECQL (0.47) | KDM1AHDAC1KDM4CERN1KMO | |
| Ethylene SCHEMBL4115800 | 0.73 | HCRTR1 (0.44) | HCRTR1HCRTR2PDE4DKDM4EALDH1A1 | |
| SCHEMBL4114573 | 0.73 | DYRK1A (0.39) | HCRTR1HCRTR2KDM1AHDAC1KDM4C | |
| SCHEMBL4117342 | 0.73 | HCRTR1 (0.45) | HCRTR1HCRTR2PDE4DKDM4EALDH1A1 | |
| SCHEMBL4114136 | 0.71 | NPC1 (0.53) | KDM4EALDH1A1NPC1 | |
| SCHEMBL27598696 | 0.70 | PDE4D (0.43) | HCRTR1HCRTR2PDE4DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494670-A1 | MEDICINE FOR TREATING CANCER | Kowa Co., Ltd. (JP) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003086397-A1 | MEDICINE FOR TREATING CANCER | KOWA CO., LTD. (JP) | 2003-10-23 | — | — | WO | disclosed |