SCHEMBL6167341

SCHEMBL6167341

CCc1ccc(COC(C)=O)nc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HRH3 Q9Y5N1 2/20 0.42
PPARG P37231 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 1/20 0.41
CYP3A4 P08684 2/20 0.41
RXRA P19793 2/20 0.41
MAPT P10636 2/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
KDM4E B2RXH2 2/20 0.40
POLB P06746 2/20 0.40
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.37
RXRB P28702 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8194734 0.94 ALDH1A1 (0.40) ALDH1A1RAB9ANPC1SMN1; SMN2HRH3
SCHEMBL11016027 0.90 ALDH1A1 (0.52) ALDH1A1RAB9ANPC1CYP1A2CYP3A4
SCHEMBL28648474 0.85 ALDH1A1 (0.43) ALDH1A1RAB9ANPC1CYP1A2CYP3A4
SCHEMBL19661185 0.84 PPARG (0.48) ALDH1A1RAB9ANPC1SMN1; SMN2HRH3
SCHEMBL13390581 0.83 ALDH1A1 (0.41) ALDH1A1RAB9ANPC1CYP1A2CYP3A4
SCHEMBL7410889 0.81 ESR1 (0.45) ALDH1A1RAB9ANPC1SMN1; SMN2CYP1A2
SCHEMBL9527654 0.80 CA12 (0.51) ALDH1A1RAB9ANPC1SMN1; SMN2CYP1A2
SCHEMBL3060324 0.79 ALDH1A1 (0.43) ALDH1A1RAB9ANPC1SMN1; SMN2CYP1A2
SCHEMBL11631724 0.79 SAE1 (0.46) ALDH1A1RAB9ANPC1SMN1; SMN2MAPT
SCHEMBL13201476 0.79 HRH3 (0.46) ALDH1A1RAB9ANPC1SMN1; SMN2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1227347-C Bleach and oxidation catalyst UNILEVER PLC (NL) 2005-11-16 CN disclosed
EP-1109965-B1 METHOD OF TREATING A TEXTILE UNILEVER PLC (GB) 2005-06-01 EP disclosed
CN-1167785-C Bleaching compositions and methods for bleaching substrates 2004-09-22 CN disclosed
EP-1109884-B1 COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2004-09-01 EP disclosed
CN-1163578-C Detergent bleaching composition 2004-08-25 CN disclosed
EP-1008645-B1 Detergent bleaching compositions UNILEVER PLC (GB) 2004-07-21 EP disclosed
CN-1158263-C Method of treating a textile 2004-07-21 CN disclosed
EP-1433840-A1 Composition and method for bleaching a substrate UNILEVER PLC (GB) 2004-06-30 EP disclosed
EP-1001009-B1 Bleach and oxidation catalyst UNILEVER PLC (GB) 2003-09-03 EP disclosed
CN-1325436-A Bleaching and oxidation catalyst UNILEVER PLC (NL) 2001-12-05 CN disclosed
EP-1008645-A1 Detergent bleaching compositions UNILEVER PLC (GB) 2000-06-14 EP disclosed
WO-2000027976-A1 BLEACH AND OXIDATION CATALYST UNILEVER PLC (GB) 2000-05-18 WO disclosed
WO-2000027975-A1 DETERGENT BLEACHING COMPOSITION UNILEVER PLC (GB) 2000-05-18 WO disclosed
EP-1001009-A1 Bleach and oxidation catalyst UNILEVER PLC (GB) 2000-05-17 EP disclosed
WO-2000012667-A1 COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2000-03-09 WO disclosed
WO-2000012808-A1 METHOD OF TREATING A TEXTILE UNILEVER PLC (GB) 2000-03-09 WO disclosed
EP-0313630-B1 SUBSTITUTED 2-ACYLPYRIDIN-ALPHA-(N)-HETARYLHYDRAZONES AND MEDICAMENTS CONTAINING SAME DEUTSCHES AUSSÄTZIGEN HILFSWERK E.V. (DE) 1992-09-16 EP disclosed
US-5084458-A Bactericides, malaria and antitumor agents SCHAPER KLAUS JUERGEN (DE) 1992-01-28 US disclosed
US-4997835-A Bactericides, malaria, antitumor SCHAPER KLAUS JUERGEN (DE) 1991-03-05 US disclosed
EP-0313630-A1 SUBSTITUTED 2-ACYLPYRIDIN-ALPHA-(N)-HETARYLHYDRAZONES AND MEDICAMENTS CONTAINING SAME. DEUTSCHES AUSSATZIGEN HILFSWER (DE) 1989-05-03 EP disclosed