SCHEMBL616752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10189441	0.95	EGFR (0.41)	EGFRHDAC3HDAC1HDAC7HDAC8
	SCHEMBL617922	0.94	HDAC3 (0.41)	HDAC3HDAC1HDAC7HDAC8HDAC6
	SCHEMBL617921	0.94	HDAC3 (0.41)	HDAC3HDAC1HDAC7HDAC8HDAC6
	SCHEMBL12118580	0.89	NPSR1 (0.50)	HDAC3HDAC1HDAC7HDAC8HDAC6
	SCHEMBL10189439	0.89	NPSR1 (0.39)	HDAC3HDAC1HDAC7HDAC8HDAC6
	SCHEMBL10240339	0.89	HDAC3 (0.44)	HDAC3HDAC1HDAC7HDAC8HDAC6
	SCHEMBL10241277	0.88	NPC1 (0.40)	HDAC3HDAC1HDAC7HDAC8HDAC6
	Hydrochloric Acid SCHEMBL616107	0.88	HDAC3 (0.43)	HDAC3HDAC1HDAC7HDAC8HDAC6
	SCHEMBL4700326	0.87	HTT (0.50)	POLBMEN1KMT2AGAATDP1
	SCHEMBL3303324	0.86	MEN1 (0.41)	HDAC3HDAC1HDAC7HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.