Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 14/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.56 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3818190 | 0.95 | OPRL1 (0.61) | OPRL1OPRM1OPRK1SLC18A3SIGMAR1 | |
| SCHEMBL3817548 | 0.86 | SLC18A3 (0.69) | OPRL1OPRM1SLC18A3SIGMAR1 | |
| SCHEMBL3825180 | 0.81 | SLC18A3 (0.63) | OPRL1OPRM1OPRK1SLC18A3SIGMAR1 | |
| SCHEMBL3816106 | 0.78 | SIGMAR1 (0.68) | OPRL1OPRM1SLC18A3SIGMAR1 | |
| SCHEMBL14467581 | 0.76 | SIGMAR1 (0.58) | OPRL1OPRM1SLC18A3SIGMAR1 | |
| SCHEMBL3810340 | 0.76 | SIGMAR1 (0.54) | OPRL1OPRM1OPRK1SLC18A3SIGMAR1 | |
| SCHEMBL12084449 | 0.74 | SIGMAR1 (0.48) | OPRL1OPRM1OPRK1SLC18A3SIGMAR1 | |
| SCHEMBL21179827 | 0.72 | OPRL1 (1.00) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL3810797 | 0.72 | SIGMAR1 (0.60) | OPRL1OPRM1OPRK1SLC18A3SIGMAR1 | |
| SCHEMBL13000734 | 0.71 | SIGMAR1 (0.65) | SLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385514-A4 | SPIROINDENE AND SPIROINDANE COMPOUNDS | EURO CELTIQUE SA (LU) | 2005-04-13 | — | — | EP | disclosed |
| EP-1385514-A1 | SPIROINDENE AND SPIROINDANE COMPOUNDS | Euro-Celtique S.A. (LU) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002085354-A1 | SPIROINDENE AND SPIROINDANE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2002-10-31 | — | — | WO | disclosed |