SCHEMBL6167747

SCHEMBL6167747

Nc1[c]ccc(-c2ccccn2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 2/20 0.45
PI4KB Q9UBF8 2/20 0.45
PIK3CD O00329 1/20 0.45
PIK3CA P42336 1/20 0.45
PIK3CG P48736 1/20 0.45
KDM4E B2RXH2 6/20 0.45
LMNA P02545 3/20 0.45
CCR1 P32246 3/20 0.45
CCR5 P51681 3/20 0.45
CCR8 P51685 3/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45
METAP1 P53582 1/20 0.45
BLM P54132 1/20 0.45
HIF1A Q16665 1/20 0.45
DOHH Q9BU89 1/20 0.45
P4HTM Q9NXG6 1/20 0.45
ALOX15 P16050 3/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
CYP2A6 P11509 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16026593 0.80 KDM4E (0.46) PI4KAPI4KBPIK3CDPIK3CAPIK3CG
SCHEMBL11533348 0.79 KDM4E (0.45) PI4KAPI4KBPIK3CDPIK3CAPIK3CG
SCHEMBL4364995 0.79 KDM4E (0.45) PI4KAPI4KBPIK3CDPIK3CAPIK3CG
SCHEMBL28596707 0.77 CYP2A6 (0.44) PI4KAPI4KBPIK3CDPIK3CAPIK3CG
SCHEMBL8043556 0.75 PDK2 (0.43) PI4KAPI4KBPIK3CDPIK3CAPIK3CG
SCHEMBL7555625 0.75 KDM4E (0.41) PI4KAPI4KBPIK3CDPIK3CAPIK3CG
SCHEMBL8061465 0.75 KDM4E (0.41) PI4KAPI4KBPIK3CDPIK3CAPIK3CG
SCHEMBL6354 0.72 KDM4E (0.56) KDM4ELMNACCR1CCR5CCR8
SCHEMBL3296186 0.72 MAOA (0.48) PI4KAPI4KBPIK3CAKDM4ELMNA
SCHEMBL29679578 0.72 KDM4E (0.62) PI4KAPI4KBPIK3CDPIK3CAPIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1542975-A2 9-CYANO-SUBSTITUTED PERYLENE-3,4-DICARBOXYLIC ACID MONOIMIDES BASF AKTIENGESELLSCHAFT (DE) 2005-06-22 EP disclosed
EP-1532210-A1 RYLENE DYES BASF AKTIENGESELLSCHAFT (DE) 2005-05-25 EP disclosed
EP-1513841-A1 1,6,9,14-TETRASUBSTITUTED TERRYLENE TETRACARBOXYLIC ACID DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 2005-03-16 EP disclosed
WO-2004029028-A2 9-CYANO-SUBSTITUTED PERYLENE-3,4-DICARBOXYLIC ACID MONOIMIDES AS DYESTUFFS BASF AKTIENGESELLSCHAFT (DE) 2004-04-08 WO disclosed
WO-2004026965-A1 RYLENE DYES BASF AKTIENGESELLSCHAFT (DE) 2004-04-01 WO disclosed
EP-1373214-A1 RYLENE DERIVATIVES AND THEIR USE AS DYES BASF AKTIENGESELLSCHAFT (DE) 2004-01-02 EP disclosed
WO-2003104232-A1 1,6,9,14-TETRASUBSTITUTED TERRYLENE TETRACARBOXYLIC ACID DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 2003-12-18 WO disclosed
WO-2002066438-A1 RYLENE DERIVATIVES AND THEIR USE AS DYES BASF AKTIENGESELLSCHAFT (DE) 2002-08-29 WO disclosed
EP-1206456-A1 THERMOCHROMIC RYLENE DYES BASF AKTIENGESELLSCHAFT (DE) 2002-05-22 EP disclosed
WO-2001016109-A1 THERMOCHROMIC RYLENE DYES BASF AKTIENGESELLSCHAFT (DE) 2001-03-08 WO disclosed
EP-0804507-A1 SUBSTITUTED QUATERRYLENE TETRACARBOXYLIC ACID DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 1997-11-05 EP disclosed
WO-1996022332-A1 SUBSTITUTED QUATERRYLENE TETRACARBOXYLIC ACID DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 1996-07-25 WO disclosed