Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14504512 | 0.80 | BCHE (0.36) | CYP1A2KMT2AALDH1A1CYP2D6MAPK1 | |
| SCHEMBL14504517 | 0.80 | BCHE (0.36) | CYP1A2KMT2AALDH1A1CYP2D6MAPK1 | |
| SCHEMBL14503982 | 0.80 | BCHE (0.36) | CYP1A2KMT2AALDH1A1CYP2D6MAPK1 | |
| SCHEMBL27735943 | 0.78 | ALDH1A1 (0.32) | CYP1A2KMT2AALDH1A1CYP2D6MAPK1 | |
| SCHEMBL9349527 | 0.78 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL28783671 | 0.78 | ALDH1A1 (0.32) | CYP1A2KMT2AALDH1A1CYP2D6MAPK1 | |
| SCHEMBL27942999 | 0.77 | KMT2A (0.38) | CYP1A2CYP3A4CYP2C9HIF1AKMT2A | |
| SCHEMBL11231831 | 0.76 | — | — | |
| SCHEMBL11235682 | 0.74 | CASR (0.40) | — | |
| SCHEMBL17673531 | 0.73 | CYP2D6 (0.35) | CYP1A2KMT2AALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133490-B1 | PIPERAZINONE DERIVATIVES | CIBA SC HOLDING AG (CH) | 2005-07-27 | — | — | EP | disclosed |
| US-6642383-B2 | Of the class 3,3,5,5-tetramethyl-2-oxo-1,4-piperazine, polymers thereof; stabilizers for thermoplastic organic polymers, coating compositions or photographic materials | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-11-04 | — | — | US | disclosed |
| US-6596461-B1 | Useful for stabilizing an organic material against degradation induced by light, heat or oxidation | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-22 | — | — | US | disclosed |
| US-20020115859-A1 | Oxopiperazinyl derivatives and light stabilized compositions | LAZZARI DARIO (IT) | 2002-08-22 | — | — | US | disclosed |
| EP-1133490-A1 | PIPERAZINONE DERIVATIVES | Ciba SC Holding AG (CH) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000031069-A1 | PIPERAZINONE DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-06-02 | — | — | WO | disclosed |
| US-4226963-A | Process for the stereoregular polymerization of alpha-olephins | MONTEDISON S.P.A. (IT) | 1980-10-07 | — | — | US | disclosed |
| US-4107413-A | Process for the stereoregular polymerization of alpha olefins | MONTEDISON S.P.A. (IT) | 1978-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115859-A1 | Oxopiperazinyl derivatives and light stabilized compositions | CBR1, PYM1, CCT4 | CYP1A2 1593/4885CYP3A4 2520/4885CYP2C9 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.