Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167841 | 1.00 | KCNH2 (0.51) | KCNH2MAPTPDE7ACNR1LMNA | |
| SCHEMBL6167833 | 1.00 | KCNH2 (0.51) | KCNH2MAPTPDE7ACNR1LMNA | |
| SCHEMBL6172086 | 0.93 | KCNH2 (0.53) | KCNH2MAPTCNR1KCNA5MEN1 | |
| SCHEMBL6172074 | 0.93 | KCNH2 (0.53) | KCNH2MAPTCNR1KCNA5MEN1 | |
| SCHEMBL6172081 | 0.93 | KCNH2 (0.53) | KCNH2MAPTCNR1KCNA5MEN1 | |
| SCHEMBL6165727 | 0.92 | KCNH2 (0.52) | KCNH2MAPTLMNAMAPK1KCNA5 | |
| SCHEMBL6165740 | 0.92 | KCNH2 (0.52) | KCNH2MAPTLMNAMAPK1KCNA5 | |
| SCHEMBL6165735 | 0.92 | KCNH2 (0.52) | KCNH2MAPTLMNAMAPK1KCNA5 | |
| SCHEMBL6163878 | 0.91 | KCNH2 (0.51) | KCNH2MAPTKCNA5KMT2ANPSR1 | |
| SCHEMBL6163891 | 0.91 | KCNH2 (0.51) | KCNH2MAPTKCNA5KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212314-B1 | BENZOPYRAN DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-6589983-B1 | Antiarrhythmic agents having the prolongation effect on the functional refractory period as a main function | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-08 | — | — | US | disclosed |