Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.38 |
| ▸ | TLR3 | O15455 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172081 | 1.00 | KCNH2 (0.53) | KCNH2KCNA5TLR3MAPTKMT2A | |
| SCHEMBL6172074 | 1.00 | KCNH2 (0.53) | KCNH2KCNA5TLR3MAPTKMT2A | |
| SCHEMBL6165727 | 0.94 | KCNH2 (0.52) | KCNH2KCNA5MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6165735 | 0.94 | KCNH2 (0.52) | KCNH2KCNA5MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6165740 | 0.94 | KCNH2 (0.52) | KCNH2KCNA5MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6167833 | 0.93 | KCNH2 (0.51) | KCNH2KCNA5MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6163878 | 0.93 | KCNH2 (0.51) | KCNH2KCNA5MAPTKMT2ANPSR1 | |
| SCHEMBL6167849 | 0.93 | KCNH2 (0.51) | KCNH2KCNA5MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6163891 | 0.93 | KCNH2 (0.51) | KCNH2KCNA5MAPTKMT2ANPSR1 | |
| SCHEMBL6167841 | 0.93 | KCNH2 (0.51) | KCNH2KCNA5MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212314-B1 | BENZOPYRAN DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-6589983-B1 | Antiarrhythmic agents having the prolongation effect on the functional refractory period as a main function | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-08 | — | — | US | disclosed |