Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP3 | P08254 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13879409 | 0.79 | ITGAL (0.49) | ELANEMGLLITGALTSHRALDH1A1 | |
| SCHEMBL6167711 | 0.76 | CNR1 (0.50) | MGLLLMNACNR1MMP2MMP3 | |
| SCHEMBL11569756 | 0.76 | ELANE (0.61) | ELANELMNAITGALMAPK1ALDH1A1 | |
| SCHEMBL6169639 | 0.76 | CNR1 (0.47) | ELANEMGLLLMNACNR1MMP2 | |
| SCHEMBL6168870 | 0.75 | GAA (0.46) | MGLLLMNACNR1MMP2MMP3 | |
| SCHEMBL6169738 | 0.74 | CNR1 (0.43) | MGLLLMNACNR1MMP2MMP3 | |
| SCHEMBL13879502 | 0.73 | ITGAL (0.61) | ELANELMNACNR1ITGALALDH1A1 | |
| SCHEMBL6169740 | 0.72 | CNR1 (0.69) | MGLLLMNACNR1MMP2MMP3 | |
| SCHEMBL1191959 | 0.72 | AR (0.55) | MGLLLMNAMMP2MMP3MMP9 | |
| SCHEMBL13879421 | 0.72 | ITGAL (0.50) | ELANEMGLLMCHR1ITGALALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546111-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031160-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-04-15 | — | — | WO | disclosed |