Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167938 | 0.90 | PPARD (0.41) | PPARDPPARAPPARG | |
| SCHEMBL6166880 | 0.87 | PPARD (0.57) | PPARDPPARAPPARG | |
| Hydrochloric Acid SCHEMBL5861852 | 0.87 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL6164059 | 0.86 | PPARD (0.43) | PPARDPPARAPPARG | |
| SCHEMBL6168010 | 0.85 | PPARD (0.40) | PPARDPPARAPPARG | |
| SCHEMBL5861914 | 0.84 | PPARD (0.43) | PPARDPPARAPPARG | |
| SCHEMBL5862035 | 0.81 | PRMT1 (0.40) | HDAC1 | |
| SCHEMBL6164377 | 0.80 | PPARD (0.41) | PPARDPPARAPPARG | |
| SCHEMBL6167419 | 0.79 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL6167231 | 0.79 | PPARD (0.47) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | claimed |