Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CLK2 | P49760 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 5/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6505726 | 0.90 | KCNH2 (0.72) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL8385634 | 0.89 | KCNH2 (0.56) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL3551443 | 0.89 | ALDH1A1 (0.57) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL3551445 | 0.89 | ALDH1A1 (0.57) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL2670480 | 0.87 | KCNH2 (0.55) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL4750067 | 0.87 | KCNH2 (0.55) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9779913 | 0.87 | KCNH2 (0.55) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL6529669 | 0.87 | KCNH2 (0.67) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL6159445 | 0.86 | KDM4E (0.66) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL8383857 | 0.86 | KCNH2 (0.57) | KCNH2ALDH1A1POLBOPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919553-B1 | cis-SUBSTITUTED AMINOCYCLOPROPANE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2005-03-02 | — | — | EP | disclosed |
| US-5476950-A | Aminopyrrolidine compound | DAIICHI SEIYAKU CO., LTD. (JP) | 1995-12-19 | — | — | US | disclosed |
| US-5380874-A | Pyrrolidine carbamates | DAIICHI SEIYAKU CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0207420-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-5098912-A | Bactericides for grampositive bacteria | DAIICHI SEIYAKU CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0207420-A2 | Pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1987-01-07 | — | — | EP | disclosed |