Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | MC1R | Q01726 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887760 | 0.77 | EPHX1 (0.50) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5197498 | 0.76 | KDM4E (0.34) | ALDH1A1ATMOPRM1OPRL1MEN1 | |
| SCHEMBL3091643 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TSHRATMOPRM1OPRL1 | |
| SCHEMBL11863846 | 0.75 | TSHR (0.34) | ALDH1A1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL5194049 | 0.73 | MC4R (0.60) | ALDH1A1MC4RMC3RMC1RMEN1 | |
| Water SCHEMBL28019795 | 0.73 | TSHR (0.37) | TSHR | |
| SCHEMBL7735127 | 0.72 | TSHR (0.35) | ALDH1A1TSHR | |
| SCHEMBL5473307 | 0.72 | TSHR (0.35) | ALDH1A1TSHR | |
| SCHEMBL1310115 | 0.72 | CYP3A4 (0.37) | ALDH1A1TSHRMC4RMC3RMC1R | |
| SCHEMBL31382688 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499588-A1 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003093234-A1 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-13 | — | — | WO | disclosed |