Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168801 | 0.90 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL5698527 | 0.89 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL6167959 | 0.87 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL27497977 | 0.84 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL6171523 | 0.81 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL7495715 | 0.80 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL6170018 | 0.79 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL6168610 | 0.79 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL8473865 | 0.79 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL6170748 | 0.78 | PTGS2 (0.55) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1528059-A2 | Substituted isoxazoles for the treatment of inflammation | G.D. Searle LLC (US) | 2005-05-04 | — | — | EP | disclosed |
| EP-1223167-A2 | Substituted isoxazoles for the treatment of inflammation | G.D. Searle & Co. (US) | 2002-07-17 | — | — | EP | disclosed |
| US-5985902-A | TREATING INFLAMMATION AND INFLAMMATION-ASSOCIATED DISORDERS, SUCH AS ARTHRITIS | G.D. SEARLE & CO. (US) | 1999-11-16 | — | — | US | disclosed |
| US-5859257-A | ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0809636-A1 | SUBSTITUTED ISOXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-12-03 | — | — | EP | disclosed |
| US-5633272-A | Substituted isoxazoles for the treatment of inflammation | PHARMACIA & UPJOHN COMPANY LLC | 1997-05-27 | — | — | US | disclosed |
| WO-1996025405-A1 | SUBSTITUTED ISOXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-22 | — | — | WO | disclosed |