Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | IDE | P14735 | 1/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168779 | 0.78 | SMN1; SMN2 (0.51) | POLBSMN1; SMN2ALDH1A1MEN1MAPT | |
| SCHEMBL6170954 | 0.77 | — | — | |
| SCHEMBL6167353 | 0.75 | — | — | |
| SCHEMBL6207829 | 0.69 | — | — | |
| SCHEMBL6167566 | 0.67 | SMN1; SMN2 (0.42) | POLBSMN1; SMN2ALDH1A1MEN1MAPT | |
| SCHEMBL6169495 | 0.67 | POLB (0.42) | POLBSMN1; SMN2ALDH1A1MEN1MAPT | |
| SCHEMBL6167761 | 0.67 | POLB (0.42) | POLBSMN1; SMN2ALDH1A1MEN1MAPT | |
| SCHEMBL6169230 | 0.66 | POLB (0.47) | POLBSMN1; SMN2ALDH1A1MEN1MAPT | |
| SCHEMBL6168118 | 0.66 | POLB (0.41) | POLBSMN1; SMN2ALDH1A1MEN1MAPT | |
| SCHEMBL17049309 | 0.65 | CYP19A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1498109-A1 | Furan derivatives and dyeing composition comprising a furan derivative as coupler | L'OREAL (FR) | 2005-01-19 | — | — | EP | claimed |
| EP-1498109-A1 | Furan derivatives and dyeing composition comprising a furan derivative as coupler | L'OREAL (FR) | 2005-01-19 | — | — | EP | disclosed |