Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167566 | 0.82 | SMN1; SMN2 (0.42) | POLBSMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL6169228 | 0.75 | POLB (0.38) | POLBSMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL6169495 | 0.74 | POLB (0.42) | POLBSMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL6167761 | 0.74 | POLB (0.42) | POLBSMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL6168779 | 0.74 | SMN1; SMN2 (0.51) | POLBSMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL6168118 | 0.73 | POLB (0.41) | POLBSMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL6168559 | 0.71 | KDM4E (0.31) | MAPTALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL6170989 | 0.69 | TOP2A (0.30) | GAA | |
| SCHEMBL5516786 | 0.67 | ALDH1A1 (0.42) | POLBMAPTALDH1A1HPGDLMNA | |
| SCHEMBL43388 | 0.67 | ALDH1A1 (0.42) | POLBMAPTALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1498109-A1 | Furan derivatives and dyeing composition comprising a furan derivative as coupler | L'OREAL (FR) | 2005-01-19 | — | — | EP | claimed |
| EP-1498109-A1 | Furan derivatives and dyeing composition comprising a furan derivative as coupler | L'OREAL (FR) | 2005-01-19 | — | — | EP | disclosed |