Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169259 | 0.84 | HDAC8 (0.52) | PTPN1MAPTHDAC8ALDH1A1GAA | |
| SCHEMBL6168036 | 0.81 | LMNA (0.46) | MAPTMGLLALDH1A1POLBMEN1 | |
| SCHEMBL6170720 | 0.79 | PTPN1 (0.50) | PTPN1MAPTHDAC8ALDH1A1POLB | |
| SCHEMBL6170460 | 0.79 | FLT1 (0.47) | MAPTALDH1A1POLBMEN1GAA | |
| SCHEMBL6171685 | 0.78 | BCL2L1 (0.54) | POLBMEN1RAB9AKMT2A | |
| SCHEMBL6172330 | 0.78 | HDAC8 (0.54) | HDAC8 | |
| SCHEMBL6172767 | 0.76 | HDAC8 (0.52) | MAPTHDAC8MEN1KMT2A | |
| SCHEMBL6168605 | 0.74 | HDAC1 (0.50) | HDAC8 | |
| SCHEMBL1178194 | 0.73 | HDAC1 (0.47) | PTPN1MAPTPKMHDAC8 | |
| SCHEMBL6169334 | 0.72 | IDO1 (0.42) | PTPN1HDAC8GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882718-B1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-6352985-B1 | CARDIOVASCULAR DISORDERS OR GASTROINTESTINAL DISORDERS, DIABETES (TYPE II DIABETES), DIABETIC COMPLICATIONS METHOD FOR LOWERING THE BLOOD SUGAR LEVEL OF A PATIENT, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| US-6166219-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0882718-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |