Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9881652 | 0.81 | MAPK1 (0.45) | MAPK1TP53ALOX12CYP1A2TSHR | |
| SCHEMBL6580348 | 0.80 | MAPK1 (0.47) | MAPK1TP53ALOX12CYP1A2TSHR | |
| SCHEMBL9920433 | 0.80 | MAPK1 (0.44) | MAPK1TP53ALOX12CYP1A2TSHR | |
| SCHEMBL22402939 | 0.79 | MAPK1 (0.42) | MAPK1TP53ALOX12CYP1A2TSHR | |
| SCHEMBL23990683 | 0.77 | MAPK1 (0.41) | MAPK1TP53ALOX12CYP1A2ALDH1A1 | |
| SCHEMBL24597135 | 0.77 | MAPK1 (0.41) | MAPK1TP53ALOX12CYP1A2TSHR | |
| SCHEMBL11776322 | 0.76 | MAPK1 (0.51) | MAPK1TP53ALOX12TSHRALDH1A1 | |
| SCHEMBL11778347 | 0.76 | MAPK1 (0.69) | MAPK1TSHRALDH1A1LMNAKMT2A | |
| SCHEMBL16198632 | 0.74 | MAPK1 (0.45) | MAPK1TP53ALOX12ALDH1A1LMNA | |
| SCHEMBL18839755 | 0.73 | MAPK1 (0.44) | MAPK1TP53ALOX12CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964861-B1 | PROCESS FOR THE PRODUCTION OF TETRAZOLYLBENZOPYRANS | SMITHKLINE BEECHAM PLC (GB) | 2005-04-27 | — | — | EP | disclosed |
| US-6069257-A | Process for the production of tetrazolylbenzopyrans | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-05-30 | — | — | US | disclosed |