Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582834 | 0.86 | MAPK1 (0.44) | MAPK1TP53ALOX12HSD17B10PKM | |
| SCHEMBL9881652 | 0.80 | MAPK1 (0.45) | MAPK1TP53ALOX12CYP1A2ALDH1A1 | |
| SCHEMBL6169210 | 0.80 | MAPK1 (0.45) | MAPK1TP53ALOX12HSD17B10CYP1A2 | |
| SCHEMBL9920433 | 0.79 | MAPK1 (0.44) | MAPK1TP53ALOX12CYP1A2ALDH1A1 | |
| SCHEMBL11778347 | 0.78 | MAPK1 (0.69) | MAPK1HSD17B10PKMATMALDH1A1 | |
| SCHEMBL22402939 | 0.77 | MAPK1 (0.42) | MAPK1TP53ALOX12CYP1A2ALDH1A1 | |
| SCHEMBL23990683 | 0.76 | MAPK1 (0.41) | MAPK1TP53ALOX12HSD17B10CYP1A2 | |
| SCHEMBL24597135 | 0.76 | MAPK1 (0.41) | MAPK1TP53ALOX12CYP1A2ALDH1A1 | |
| SCHEMBL11776322 | 0.75 | MAPK1 (0.51) | MAPK1TP53ALOX12ALDH1A1LMNA | |
| SCHEMBL16198632 | 0.72 | MAPK1 (0.45) | MAPK1TP53ALOX12ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |