Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | INMT | O95050 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3492650 | 0.80 | GAA (0.54) | ALDH1A1GAAL3MBTL1KDM4EPOLB | |
| SCHEMBL12566554 | 0.78 | GAA (0.48) | ALDH1A1GAAL3MBTL1KDM4EALOX15 | |
| SCHEMBL9328091 | 0.74 | GAA (0.45) | GAAL3MBTL1KDM4EALOX15POLB | |
| SCHEMBL10964562 | 0.74 | GAA (0.40) | GAAL3MBTL1ALOX15POLBSMN1; SMN2 | |
| SCHEMBL12208453 | 0.73 | GAA (0.42) | GAAL3MBTL1ALOX15POLBINMT | |
| SCHEMBL7148826 | 0.73 | GAA (0.46) | GAAL3MBTL1KDM4EALOX15POLB | |
| SCHEMBL13621180 | 0.72 | KDM4E (0.41) | ALDH1A1PKMGAAL3MBTL1KDM4E | |
| SCHEMBL11227178 | 0.71 | KDM4E (0.44) | ALDH1A1PKMGAAL3MBTL1KDM4E | |
| SCHEMBL6468845 | 0.71 | GAA (0.45) | GAAL3MBTL1KDM4EPOLBMEN1 | |
| SCHEMBL11225104 | 0.70 | GAA (0.42) | GAAL3MBTL1KDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1495020-A1 | N-(MORPHOLIN-2YL) METHYL ACETAMIDE DERIVATIVES AS CCR-3 ANTAGONISTS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003082863-A1 | N-(MORPHOLIN-2YL) METHYL ACETAMIDE DERIVATIVES AS CCR-3 ANTAGONISTS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2003-10-09 | — | — | WO | disclosed |