SCHEMBL11227178

SCHEMBL11227178

O=C(O)CCN1CCN(CCC(=O)O)C1=S

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.44
▸ POLB P06746 2/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ MAPT P10636 2/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ CYP1A2 P05177 2/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ APEX1 P27695 2/20 0.41
▸ GLA P06280 1/20 0.41
▸ ALOX15 P16050 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ SIRT1 Q96EB6 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.38
▸ MAPK1 P28482 2/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ PKM P14618 1/20 0.38
▸ S1PR1 P21453 1/20 0.36
▸ EGLN3 Q9H6Z9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11226068 0.88 KDM4E (0.40) KDM4EPOLBMEN1KMT2AMAPT
SCHEMBL14273139 0.82 S1PR1 (0.50) KDM4EPOLBMEN1KMT2AMAPT
SCHEMBL4278206 0.74 CYP1A2 (0.50) KDM4EPOLBMEN1KMT2AMAPT
SCHEMBL7504798 0.71 KMT2A (0.51) KDM4EPOLBMEN1KMT2AMAPT
SCHEMBL24682237 0.71 HSD17B10 (0.52) KDM4EPOLBMEN1KMT2ACYP1A2
SCHEMBL6169212 0.71 ALDH1A1 (0.46) KDM4EPOLBMEN1KMT2AMAPT
SCHEMBL13621180 0.70 KDM4E (0.41) KDM4EPOLBMEN1KMT2AMAPT
SCHEMBL23586853 0.69 KDM4E (0.38) KDM4EPOLBMEN1KMT2AMAPT
SCHEMBL443220 0.68 TSHR (0.53) KDM4EPOLBMEN1KMT2AMAPT
SCHEMBL6070489 0.68 KMT2A (0.44) KDM4EPOLBMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4343880-A Dye-forming electrically activatable recording material and process EASTMAN KODAK COMPANY (US) 1982-08-10 — — US disclosed
US-4201582-A MERCAPTO HETEROCYCLIC TONER, SILVER HALIDE, SILVER SALT OF CARBOXYALKYL HETEROCYCLIC THIONE, ORGANIC REDUCING AGNET EASTMAN KODAK COMPANY (US) 1980-05-06 — — US disclosed
US-4186009-A SILVER HALIDE, SILVER SALT OXIDIZING AGENT, ORGANIC REDUCING AGENT, HYDRAZINO THIOUREA NUCLEATING AGENT EASTMAN KODAK COMPANY (US) 1980-01-29 — — US disclosed
US-4168170-A NONCATALYTIC PHOTOTHERMOGRAPHY EASTMAN KODAK COMPANY (US) 1979-09-18 — — US disclosed
US-4168169-A SUBSTITUTED THIAZOLINE, OXAZOLINE, OR IMIDAZOLINE SILVER HALIDE COMPLEXING AGENT EASTMAN KODAK COMPANY (US) 1979-09-18 — — US disclosed
US-4105451-A 2-MERCAPTO-BENZOTHIAZOLE, -BENZOXAZOLE, -BENZIMIDAZOLE OR -BENZOSELENAZOLE; HETEROCYCLIC THIONE SILVER SALT; REDUCING AGENT; BINDER; SILVER HALIDE AND SENSITIZER EASTMAN KODAK COMPANY (US) 1978-08-08 — — US disclosed
US-4022617-A DIFFUSION EASTMAN KODAK COMPANY (US) 1977-05-10 — — US disclosed
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