Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.57 |
| ▸ | CTSS | P25774 | 5/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701719 | 0.86 | CTSK (0.61) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6171112 | 0.84 | CTSK (0.59) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6171324 | 0.82 | CTSK (0.57) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5514723 | 0.77 | CTSK (0.51) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5518361 | 0.76 | CTSK (0.61) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5516815 | 0.76 | CTSK (0.61) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6172062 | 0.76 | CTSK (0.49) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5523799 | 0.74 | CTSK (0.59) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5516948 | 0.74 | CTSK (0.56) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5518535 | 0.74 | CTSK (0.58) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537074-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA INC. (CA) | 2005-06-08 | — | — | EP | claimed |
| WO-2004022526-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2004-03-18 | — | — | WO | claimed |
| EP-1537074-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA INC. (CA) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004022526-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2004-03-18 | — | — | WO | disclosed |