Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.62 |
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 5/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173590 | 0.89 | F2 (0.75) | F2ESR1ESR2HTT | |
| SCHEMBL6171329 | 0.88 | F2 (0.79) | F2ESR1ESR2HTT | |
| SCHEMBL7990598 | 0.88 | F2 (0.60) | F2LTA4HESR1ESR2ITGA4 | |
| SCHEMBL7985980 | 0.88 | F2 (0.60) | F2LTA4HESR1ESR2ITGA4 | |
| Oxalic Acid SCHEMBL6173739 | 0.85 | F2 (0.57) | F2ESR1ESR2ITGA4HTT | |
| SCHEMBL7768104 | 0.83 | F2 (0.68) | F2LTA4HESR1ESR2 | |
| SCHEMBL7413476 | 0.82 | F2 (0.69) | F2LTA4HESR1ESR2ITGA4 | |
| SCHEMBL6597917 | 0.82 | F2 (0.71) | F2LTA4HESR1ESR2ITGA4 | |
| SCHEMBL7412678 | 0.82 | F2 (0.70) | F2ESR1ESR2 | |
| SCHEMBL7774139 | 0.82 | F2 (0.68) | F2LTA4HESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-01-05 | — | — | EP | disclosed |
| US-6391901-B1 | Thrombin inhibitors | ELI LILLY AND COMPANY | 2002-05-21 | — | — | US | disclosed |
| US-6284756-B1 | ANTICOAGULANT | ELI LILLY AND COMPANY | 2001-09-04 | — | — | US | disclosed |