Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.75 |
| ▸ | ESR1 | P03372 | 12/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | PLD2 | O14939 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | C5 | P01031 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621321 | 0.90 | F2 (0.91) | F2ESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL6170586 | 0.89 | F2 (0.62) | F2ESR1ESR2HTT | |
| SCHEMBL6836522 | 0.89 | F2 (0.89) | F2ESR1ESR2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7675008 | 0.89 | F2 (0.89) | F2ESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL7768035 | 0.89 | F2 (0.93) | F2ESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL7412678 | 0.89 | F2 (0.70) | F2ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL8102638 | 0.88 | F2 (0.81) | F2ESR1ESR2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5858600 | 0.88 | F2 (0.88) | F2ESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL6171204 | 0.88 | F2 (0.75) | F2ESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL7411720 | 0.88 | F2 (0.75) | F2ESR1ESR2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-01-05 | — | — | EP | disclosed |
| US-6391901-B1 | Thrombin inhibitors | ELI LILLY AND COMPANY | 2002-05-21 | — | — | US | disclosed |
| US-6284756-B1 | ANTICOAGULANT | ELI LILLY AND COMPANY | 2001-09-04 | — | — | US | disclosed |