SCHEMBL6170616

SCHEMBL6170616

Nc1ccccc1OC(=O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.63
MAPT P10636 6/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
TSHR P16473 2/20 0.61
SLC6A3 Q01959 1/20 0.56
GAA P10253 3/20 0.54
ESR1 P03372 2/20 0.54
ESR2 Q92731 2/20 0.54
HSD17B10 Q99714 2/20 0.54
MEN1 O00255 2/20 0.54
JAK2 O60674 1/20 0.54
USP2 O75604 1/20 0.54
ALOX15 P16050 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
LMNA P02545 2/20 0.50
F2 P00734 1/20 0.50
METAP2 P50579 1/20 0.50
METAP1 P53582 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
PARP10 Q53GL7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31119217 1.00 KMT2A (0.63) KMT2AMAPTSMN1; SMN2TSHRSLC6A3
SCHEMBL13292717 0.94 SMN1; SMN2 (0.63) KMT2AMAPTSMN1; SMN2TSHRSLC6A3
SCHEMBL13292734 0.89 SMN1; SMN2 (0.58) KMT2AMAPTSMN1; SMN2TSHRSLC6A3
SCHEMBL13292712 0.89 SMN1; SMN2 (0.62) KMT2AMAPTSMN1; SMN2TSHRSLC6A3
SCHEMBL10633834 0.89 KMT2A (0.59) KMT2AMAPTSMN1; SMN2TSHRSLC6A3
SCHEMBL30335393 0.85 KMT2A (0.56) KMT2AMAPTSMN1; SMN2TSHRSLC6A3
SCHEMBL725404 0.85 KMT2A (0.76) KMT2AMAPTSMN1; SMN2TSHRSLC6A3
SCHEMBL13292735 0.84 SMN1; SMN2 (0.57) KMT2AMAPTSMN1; SMN2TSHRSLC6A3
SCHEMBL13292725 0.83 SMN1; SMN2 (0.65) KMT2AMAPTSMN1; SMN2TSHRSLC6A3
Hydrochloric Acid SCHEMBL16050041 0.83 KMT2A (0.73) KMT2AMAPTSMN1; SMN2TSHRSLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103373967-A Synthetic method of shenqinmycin DALIAN JOIN KING BIO CHEMICAL TECHNOLOGY CO LTD 2013-10-30 CN claimed
CN-117700990-A Resin composition, adhesive, coating agent, cured product, adhesive sheet, resin-coated copper foil, copper-clad laminate, and printed wiring board 荒川化学工业株式会社 2024-03-15 CN disclosed
CN-108690194-A Polyimides, adhesive, adhesive material, adhesive layer, sheet adhesive, copper foil, copper-clad laminated board, wiring plate and manufacturing method 荒川化学工业株式会社 2018-10-23 CN disclosed
CN-108690193-A Polyimides, adhesive, adhesive material, adhesive layer, sheet adhesive, copper foil, copper-clad laminated board, wiring plate and manufacturing method 荒川化学工业株式会社 2018-10-23 CN disclosed
CN-108690552-A Adhesive, adhesive material, adhesive layer, sheet adhesive, copper foil, copper-clad laminated board, wiring plate and manufacturing method 荒川化学工业株式会社 2018-10-23 CN disclosed
CN-107009697-A Copper foil covered stack and printed wiring board 荒川化学工业株式会社 2017-08-04 CN disclosed
CN-106995678-A Polyimide adhesive 荒川化学工业株式会社 2017-08-01 CN disclosed
CN-106977716-A Resin combination, adhesive, membranaceous adhesive material, sheet adhesive, the copper foil of resin, copper-clad laminated board, wiring plate 荒川化学工业株式会社 2017-07-25 CN disclosed
CN-106947079-A Modified polyimide, adhesive compound, the Copper Foil of resin, copper-clad laminated board, printed wiring board and multilager base plate 荒川化学工业株式会社 2017-07-14 CN disclosed
CN-106010420-A Polyimide-based adhesive, film adhesive, adhesive layer, adhesive sheet, copper-clad laminate, wiring board and its manufacturing method 荒川化学工业株式会社 2016-10-12 CN disclosed
US-20100144977-A1 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2010-06-10 US disclosed
US-20100144977-A1 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2010-06-10 US disclosed
US-20090221642-A1 MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF-176 ASTRAZENECA AB (SE) 2009-09-03 US disclosed
EP-1379516-B1 ALKOXYCARBONYLAMINO BENZOIC ACID OR ALKOXYCARBONYLAMINO TETRAZOLYL PHENYL DERIVATIVES AS IP ANTAGONISTS HOFFMANN LA ROCHE (CH) 2005-11-16 EP disclosed
US-6903086-B2 Alkoxycarbonylamino benzoic acid or alkoxycarbonylamino tetrazolyl phenyl derivatives as IP antagonists SYNTEX (U.S.A.) LLC (US) 2005-06-07 US disclosed
EP-1379516-A1 ALKOXYCARBONYLAMINO BENZOIC ACID OR ALKOXYCARBONYLAMINO TETRAZOLYL PHENYL DERIVATIVES AS IP ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2004-01-14 EP disclosed
US-20020165235-A1 Alkoxycarbonylamino benzoic acid or alkoxycarbonylamino tetrazolyl phenyl derivatives as IP antagonists SYNTEX (U.S.A.) LLC 2002-11-07 US disclosed
WO-2002070500-A1 ALKOXYCARBONYLAMINO BENZOIC ACID OR ALKOXYCARBONYLAMINO TETRAZOLYL PHENYL DERIVATIVES AS IP ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2002-09-12 WO disclosed
CN-1226233-A Non-ulcer-causing analgesic/anti-inflammatory clonixin derivatives, HANDFORTH INVEST LTD (GB) 1999-08-18 CN disclosed
US-4124579-A FOR POLYMERIC MATERIALS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165235-A1 Alkoxycarbonylamino benzoic acid or alkoxycarbonylamino tetrazolyl phenyl derivatives as IP antagonists GPBAR1, GABRP, TBXA2R KMT2A 4499/4885MAPT 4798/4885SMN1; SMN2 3978/4885
US-20090221642-A1 MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF-176 CHRM1, CHRM2, CHRM3 KMT2A 2088/4885MAPT 3677/4885SMN1; SMN2 1050/4885
US-20100144977-A1 CURING AGENTS FOR EPOXY RESINS PTGER3, PTGER4, ELL KMT2A 669/4885MAPT 3745/4885SMN1; SMN2 2356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.