⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2218606 | 0.78 | — | — | |
| SCHEMBL989757 | 0.73 | — | — | |
| SCHEMBL13659927 | 0.68 | NQO1 (0.30) | — | |
| SCHEMBL2070153 | 0.68 | — | — | |
| SCHEMBL20849888 | 0.65 | — | — | |
| SCHEMBL4922604 | 0.64 | — | — | |
| SCHEMBL919240 | 0.64 | — | — | |
| SCHEMBL16421167 | 0.63 | LRRK2 (0.30) | — | |
| SCHEMBL13633756 | 0.62 | — | — | |
| SCHEMBL8273457 | 0.62 | NQO1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007824-B1 | BENZOFURANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITION CONTAINING THEM. | LABORATOIRES JACQUES LOGEAIS Société dite: (FR) | 1981-07-22 | — | — | EP | claimed |
| EP-1129071-B1 | PHENYL-SUBSTITUTED CYCLIC ENAMINONES | BAYER CROPSCIENCE AG (DE) | 2005-10-26 | — | — | EP | disclosed |
| US-20030130125-A1 | Phenyl-substituted cyclic enaminones | FISCHER REINER (DE) | 2003-07-10 | — | — | US | disclosed |
| US-6455472-B1 | HERBICIDES, ACARICIDES, NEMATICIDES AND INSECTICIDES FOR CROPS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-24 | — | — | US | disclosed |
| EP-1129071-A1 | PHENYL-SUBSTITUTED CYCLIC ENAMINONES | Bayer Aktiengesellschaft (DE) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027812-A1 | PHENYL-SUBSTITUTED CYCLIC ENAMINONES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-18 | — | — | WO | disclosed |
| US-4547502-A | Dihydropyridines and their use in treating cardiac conditions and hypertension | PFIZER INC. (US) | 1985-10-15 | — | — | US | disclosed |
| EP-0107293-A2 | Dihydropyridines | Pfizer Limited (GB) | 1984-05-02 | — | — | EP | disclosed |
| EP-0104860-A1 | 1-Phenyl-2(1H,3H)-indolone psycho-therapeutic agents | PFIZER INC. (US) | 1984-04-04 | — | — | EP | disclosed |
| US-4251542-A | Imino compounds | CIBA-GEIGY CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
| US-4130652-A | 2-(Iminoethylidene)-pyrrolidines and tautomeric 2-(aminoethenyl)-1-pyrrolines | CIBA-GEIGY CORPORATION (US) | 1978-12-19 | — | — | US | disclosed |