Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 10/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5368180 | 0.90 | OPRL1 (0.51) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL3390751 | 0.87 | OPRL1 (0.69) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL5364114 | 0.84 | OPRL1 (0.51) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL12834911 | 0.82 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL2771608 | 0.80 | CNR1 (0.63) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL5364111 | 0.78 | CNR2 (0.59) | CNR1CNR2 | |
| SCHEMBL5368177 | 0.78 | CNR1 (0.56) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL12918610 | 0.78 | CNR2 (0.59) | CNR1CNR2 | |
| SCHEMBL5596875 | 0.78 | CNR2 (0.57) | CNR1CNR2 | |
| SCHEMBL15392497 | 0.77 | CNR2 (0.57) | OPRL1KCNH2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556373-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | Pfizer Products Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004035566-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2004-04-29 | — | — | WO | disclosed |