Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.69 |
| ▸ | CNR2 | P34972 | 8/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2771608 | 0.93 | CNR1 (0.63) | OPRL1KCNH2CNR2CNR1 | |
| SCHEMBL15392497 | 0.90 | CNR2 (0.57) | OPRL1KCNH2CNR2CNR1 | |
| SCHEMBL2769818 | 0.88 | OPRL1 (0.70) | OPRL1KCNH2CNR2CNR1 | |
| SCHEMBL4845608 | 0.88 | OPRL1 (0.70) | OPRL1KCNH2CNR2CNR1 | |
| SCHEMBL6171979 | 0.87 | OPRL1 (0.53) | OPRL1KCNH2CNR2CNR1 | |
| SCHEMBL2769539 | 0.87 | OPRL1 (0.69) | OPRL1KCNH2CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL5370632 | 0.86 | OPRL1 (0.67) | OPRL1KCNH2CNR2CNR1 | |
| SCHEMBL908671 | 0.85 | OPRL1 (0.54) | OPRL1KCNH2CNR2CNR1 | |
| SCHEMBL24208708 | 0.84 | OPRL1 (0.65) | OPRL1KCNH2CNR2CNR1 | |
| SCHEMBL3742041 | 0.82 | CNR1 (0.57) | OPRL1KCNH2CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655238-B2 | MMPL3 inhibitors, compositions and uses thereof | SHANGHAITECH UNIVERSITY (CN) | 2023-05-23 | — | — | US | disclosed |
| US-11655238-B2 | MMPL3 inhibitors, compositions and uses thereof | SHANGHAITECH UNIVERSITY (CN) | 2023-05-23 | — | — | US | disclosed |
| US-20220017492-A1 | MMPL3 INHIBITORS, COMPOSITIONS AND USES THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2022-01-20 | — | — | US | disclosed |
| EP-2882715-B1 | PYRAZOLE DERIVATIVES AND THEIR USE AS LPAR5 ANTAGONISTS | SANOFI SA (FR) | 2016-11-09 | — | — | EP | disclosed |
| US-9346762-B2 | Pyrazole derivatives and their use as LPAR5 antagonists | SANOFI (FR) | 2016-05-24 | — | — | US | disclosed |
| EP-2882715-A1 | PYRAZOLE DERIVATIVES AND THEIR USE AS LPAR5 ANTAGONISTS | SANOFI (FR) | 2015-06-17 | — | — | EP | disclosed |
| US-20150141477-A1 | Pyrazole Derivatives And Their Use As LPAR5 Antagonists | SANOFI (FR) | 2015-05-21 | — | — | US | disclosed |
| WO-2013171317-A1 | PYRAZOLE DERIVATIVES AND THEIR USE AS LPAR5 ANTAGONISTS | SANOFI (FR) | 2013-11-21 | — | — | WO | disclosed |
| WO-2010020762-A1 | 1,5-DIARYL-PYRAZOLES AND THEIR USE AS CANNABINOID RECEPTOR NEUTRAL ANTAGONISTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010020762-A1 | 1,5-DIARYL-PYRAZOLES AND THEIR USE AS CANNABINOID RECEPTOR NEUTRAL ANTAGONISTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655238-B2 | MMPL3 inhibitors, compositions and uses thereof | TIMP3, AFG3L2, MMP3 | OPRL1 3496/4885KCNH2 4695/4885CNR2 4645/4885 |
| US-20220017492-A1 | MMPL3 INHIBITORS, COMPOSITIONS AND USES THEREOF | TIMP3, AFG3L2, MMP3 | OPRL1 3496/4885KCNH2 4695/4885CNR2 4645/4885 |
| US-20150141477-A1 | Pyrazole Derivatives And Their Use As LPAR5 Antagonists | LPAR5, LPAR3, LPAR1 | OPRL1 345/4885KCNH2 702/4885CNR2 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.