Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 10/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174709 | 0.91 | ADA (0.44) | ADALPAR1KDM4AKDM5AKDM4C | |
| SCHEMBL6134589 | 0.84 | ADA (0.43) | ADALPAR1 | |
| SCHEMBL6133735 | 0.83 | ADA (0.59) | ADA | |
| SCHEMBL6168401 | 0.83 | ADA (0.59) | ADAKDM4AKDM4C | |
| SCHEMBL6170502 | 0.83 | ADA (0.48) | ADAKDM5AKDM4CKDM5B | |
| SCHEMBL6133830 | 0.82 | ADA (0.42) | ADALPAR1 | |
| SCHEMBL6172025 | 0.82 | LPAR1 (0.42) | ADALPAR1KDM4AKDM4C | |
| SCHEMBL1385827 | 0.82 | ADA (0.42) | ADALPAR1 | |
| Hydrochloric Acid SCHEMBL6133945 | 0.82 | ADA (0.58) | ADA | |
| SCHEMBL6172230 | 0.82 | ADA (0.42) | ADALPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098885-B9 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-05-18 | — | — | EP | disclosed |
| EP-1098885-B1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-6359145-B1 | ADENOSINE DEAMINASE INHIBITOR; ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |