Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BIRC2 | Q13490 | 4/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668999 | 0.98 | ZDHHC7 (0.61) | ZDHHC7CA1CA2ABCB1USP2 | |
| SCHEMBL10487617 | 0.98 | ZDHHC7 (0.61) | ZDHHC7CA1CA2ABCB1USP2 | |
| SCHEMBL11725954 | 0.98 | ZDHHC7 (0.61) | ZDHHC7CA1CA2ABCB1USP2 | |
| SCHEMBL5200841 | 0.94 | CA2 (0.59) | ZDHHC7CA1CA2ABCB1USP2 | |
| SCHEMBL27431806 | 0.86 | ZDHHC7 (0.47) | ZDHHC7CA1CA2ABCB1USP2 | |
| SCHEMBL4431247 | 0.85 | CA1 (0.47) | ZDHHC7CA1CA2ABCB1USP2 | |
| SCHEMBL28264658 | 0.84 | ZDHHC7 (0.50) | ZDHHC7CA1CA2ABCB1GPR84 | |
| SCHEMBL27842968 | 0.84 | ZDHHC7 (0.50) | ZDHHC7CA1CA2ABCB1GPR84 | |
| SCHEMBL8572230 | 0.84 | ZDHHC7 (0.50) | ZDHHC7CA1CA2ABCB1GPR84 | |
| SCHEMBL17586720 | 0.83 | ZDHHC7 (0.40) | ZDHHC7CA1CA2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556372-A2 | SUBSTITUTED 4-AMINO-1-(PYRIDYLMETHYL) PIPERIDINE AS MUSCARINIC RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004041806-A2 | SUBSTITUTED 4-AMINO-1-(PYRIDYLMETHYL) PIPERIDINE AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2004-05-21 | — | — | WO | disclosed |