Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 17/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172249 | 0.91 | ESR1 (0.50) | ESR1ESR2F2 | |
| Oxalic Acid SCHEMBL6174331 | 0.90 | ESR1 (0.52) | ESR1ESR2F2 | |
| SCHEMBL6171544 | 0.89 | F2 (0.53) | ESR1ESR2F2 | |
| SCHEMBL6596715 | 0.88 | ESR1 (0.60) | ESR1ESR2F2 | |
| SCHEMBL7774110 | 0.86 | ESR1 (0.48) | ESR1ESR2F2 | |
| SCHEMBL6172260 | 0.86 | ESR1 (0.45) | ESR1ESR2F2 | |
| SCHEMBL6598702 | 0.84 | ESR1 (0.58) | ESR1ESR2F2 | |
| SCHEMBL6599474 | 0.84 | ESR1 (0.55) | ESR1ESR2F2 | |
| SCHEMBL6592408 | 0.83 | ESR1 (0.65) | ESR1ESR2F2 | |
| SCHEMBL7772141 | 0.83 | F2 (0.59) | ESR1ESR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-01-05 | — | — | EP | disclosed |
| US-6391901-B1 | Thrombin inhibitors | ELI LILLY AND COMPANY | 2002-05-21 | — | — | US | disclosed |