Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606418 | 0.77 | KMT2A (0.40) | KMT2AMEN1NPBWR1MCHR1DRD2 | |
| SCHEMBL5606206 | 0.77 | MEN1 (0.47) | KMT2AMEN1NPBWR1MCHR1DRD2 | |
| SCHEMBL5606207 | 0.77 | MEN1 (0.47) | KMT2AMEN1NPBWR1MCHR1DRD2 | |
| SCHEMBL27388628 | 0.75 | MEN1 (0.43) | KMT2AMEN1NPBWR1MCHR1DRD2 | |
| SCHEMBL8519710 | 0.74 | MEN1 (0.42) | KMT2AMEN1NPBWR1MCHR1DRD2 | |
| SCHEMBL5606898 | 0.72 | MEN1 (0.49) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL5606901 | 0.72 | MEN1 (0.49) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL8519173 | 0.70 | MEN1 (0.49) | KMT2AMEN1NPBWR1MCHR1DRD2 | |
| SCHEMBL8519165 | 0.70 | MEN1 (0.49) | KMT2AMEN1NPBWR1MCHR1DRD2 | |
| SCHEMBL5605981 | 0.70 | KMT2A (0.44) | KMT2AMEN1NPBWR1MCHR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562908-A1 | QUINOLINE DERIVATIVES | Pfizer Products Inc. (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004043929-A1 | QUINOLINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2004-05-27 | — | — | WO | disclosed |