Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.61 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6171999 | 0.99 | F2 (0.60) | F2ESR1ESR2P2RX7 | |
| SCHEMBL6174045 | 0.91 | F2 (0.56) | F2ESR1ESR2 | |
| Oxalic Acid SCHEMBL6170789 | 0.86 | F2 (0.58) | F2ESR1ESR2 | |
| Oxalic Acid SCHEMBL6171949 | 0.86 | F2 (0.57) | F2ESR1ESR2 | |
| Oxalic Acid SCHEMBL6171943 | 0.86 | F2 (0.57) | F2ESR1ESR2 | |
| SCHEMBL7444869 | 0.85 | F2 (0.75) | F2ESR1ESR2 | |
| SCHEMBL7828640 | 0.85 | P2RX7 (0.43) | F2ESR1ESR2P2RX7 | |
| SCHEMBL6595431 | 0.80 | F2 (0.81) | F2ESR1ESR2 | |
| SCHEMBL6172369 | 0.78 | F2 (0.55) | F2ESR1ESR2 | |
| Oxalic Acid SCHEMBL6169916 | 0.77 | F2 (0.68) | F2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-01-05 | — | — | EP | claimed |
| US-6391901-B1 | Thrombin inhibitors | ELI LILLY AND COMPANY | 2002-05-21 | — | — | US | claimed |
| EP-1027051-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-01-05 | — | — | EP | disclosed |
| US-6391901-B1 | Thrombin inhibitors | ELI LILLY AND COMPANY | 2002-05-21 | — | — | US | disclosed |