Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475190 | 0.85 | IMPDH2 (0.85) | IMPDH2 | |
| SCHEMBL1475776 | 0.85 | IMPDH2 (0.78) | IMPDH2 | |
| SCHEMBL1473597 | 0.81 | IMPDH2 (0.65) | IMPDH2 | |
| SCHEMBL1475820 | 0.77 | IMPDH2 (1.00) | IMPDH2 | |
| SCHEMBL1473135 | 0.76 | IMPDH2 (1.00) | IMPDH2 | |
| SCHEMBL1472762 | 0.74 | IMPDH2 (1.00) | IMPDH2 | |
| SCHEMBL1473282 | 0.74 | IMPDH2 (0.81) | IMPDH2 | |
| SCHEMBL1328549 | 0.74 | GAA (0.50) | IMPDH2 | |
| SCHEMBL1473618 | 0.72 | IMPDH2 (0.83) | IMPDH2 | |
| SCHEMBL1473232 | 0.71 | IMPDH2 (1.00) | IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126843-A4 | COMPOUNDS DERIVED FROM AN AMINE NUCLEUS THAT ARE INHIBITORS OF IMPDH ENZYME | BRISTOL MYERS SQUIBB CO (US) | 2005-06-15 | — | — | EP | disclosed |
| US-6399773-B1 | AUTOIMMUNE DISEASE; TRANSPLANTING ORGANS | BRISTOL-MYERS SQUIBB CO. | 2002-06-04 | — | — | US | disclosed |
| EP-1126843-A1 | COMPOUNDS DERIVED FROM AN AMINE NUCLEUS THAT ARE INHIBITORS OF IMPDH ENZYME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025780-A1 | COMPOUNDS DERIVED FROM AN AMINE NUCLEUS THAT ARE INHIBITORS OF IMPDH ENZYME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-05-11 | — | — | WO | disclosed |