Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 12/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172659 | 0.90 | ADA (0.50) | ADA | |
| SCHEMBL6172982 | 0.86 | ADA (0.47) | ADANR3C2SIRT2 | |
| SCHEMBL7670504 | 0.82 | ADA (0.75) | ADA | |
| SCHEMBL6170851 | 0.81 | ADA (0.63) | ADASMN1; SMN2 | |
| SCHEMBL6168422 | 0.80 | ADA (0.68) | ADA | |
| SCHEMBL7670511 | 0.80 | ADA (0.50) | ADANR3C2 | |
| SCHEMBL7656859 | 0.73 | ADA (0.68) | ADA | |
| SCHEMBL7452591 | 0.72 | ADA (0.66) | ADA | |
| SCHEMBL28940615 | 0.72 | TAAR1 (0.47) | NR3C2POLB | |
| SCHEMBL7451699 | 0.72 | NR3C2 (0.40) | NR3C2SIRT2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098885-B9 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-05-18 | — | — | EP | disclosed |
| EP-1098885-B1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-6359145-B1 | ADENOSINE DEAMINASE INHIBITOR; ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |