Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 17/20 | 0.45 |
| ▸ | AOC1 | P19801 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172473 | 0.86 | IGF1R (0.42) | IGF1RNTRK1 | |
| SCHEMBL6174742 | 0.86 | IGF1R (0.40) | IGF1RNTRK1 | |
| SCHEMBL6172191 | 0.85 | AOC1 (0.38) | AOC1AOC3NTRK1 | |
| SCHEMBL6172456 | 0.85 | IGF1R (0.42) | IGF1RNTRK1 | |
| SCHEMBL6174374 | 0.85 | IGF1R (0.48) | IGF1RNTRK1 | |
| SCHEMBL6174069 | 0.85 | IGF1R (0.48) | IGF1R | |
| SCHEMBL6175503 | 0.85 | IGF1R (0.48) | IGF1RNTRK1 | |
| SCHEMBL6176020 | 0.85 | IGF1R (0.40) | IGF1RAOC1AOC3 | |
| SCHEMBL6173351 | 0.84 | IGF1R (0.41) | IGF1RNTRK1 | |
| SCHEMBL6172562 | 0.84 | IGF1R (0.47) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |