Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 5/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ortho-Phthalaldehyde SCHEMBL28300091 | 0.70 | LMNA (0.77) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL6738745 | 0.70 | — | — | |
| SCHEMBL1773919 | 0.69 | CYP2A6 (0.44) | ALDH1A1CYP2A6KDM4EHSD17B10ALDH5A1 | |
| SCHEMBL6849341 | 0.68 | DRD1 (0.53) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL25288128 | 0.67 | CYP2A6 (0.58) | ALDH1A1CYP2A6KDM4EHSD17B10ALDH5A1 | |
| SCHEMBL1666706 | 0.67 | CYP2A6 (0.58) | ALDH1A1CYP2A6KDM4EHSD17B10ALDH5A1 | |
| SCHEMBL976904 | 0.67 | CYP2A6 (0.58) | ALDH1A1CYP2A6KDM4EHSD17B10ALDH5A1 | |
| SCHEMBL27335985 | 0.67 | CYP2A6 (0.58) | ALDH1A1CYP2A6KDM4EHSD17B10ALDH5A1 | |
| SCHEMBL12212922 | 0.67 | DRD1 (0.51) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL15068163 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1264826-B1 | NOVEL IMIDAZOLINE COMPOUNDS | BANYU PHARMA CO LTD (JP) | 2005-03-30 | — | — | EP | disclosed |
| EP-1264826-A1 | NOVEL IMIDAZOLINE COMPOUNDS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |