Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCR9 | P51686 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177613 | 0.90 | IGF1R (0.41) | MAPTCYP2C9THRBIGF1RKMT2A | |
| SCHEMBL6224943 | 0.90 | CCR9 (0.46) | MAPTCYP2C9THRBKMT2ACCR9 | |
| SCHEMBL6174113 | 0.88 | IGF1R (0.40) | MAPTCYP2C9THRBIGF1RKMT2A | |
| SCHEMBL6174555 | 0.87 | IGF1R (0.40) | MAPTCYP2C9IGF1RKMT2ATP53 | |
| SCHEMBL6176685 | 0.86 | IGF1R (0.39) | MAPTCYP2C9THRBIGF1RKMT2A | |
| SCHEMBL6171635 | 0.85 | IGF1R (0.38) | CYP2C9IGF1RKMT2ATP53GAA | |
| SCHEMBL6171779 | 0.85 | IGF1R (0.40) | MAPTCYP2C9THRBIGF1RKMT2A | |
| SCHEMBL6171403 | 0.85 | IGF1R (0.43) | MAPTCYP2C9THRBIGF1RKMT2A | |
| SCHEMBL6176020 | 0.84 | IGF1R (0.40) | MAPTCYP2C9IGF1RKMT2ATP53 | |
| SCHEMBL6173238 | 0.84 | IGF1R (0.41) | IGF1RKMT2ATP53PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |