Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.44 |
| ▸ | FNTB | P49356 | 13/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735112 | 0.92 | FNTA (0.52) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6172596 | 0.90 | FNTA (0.49) | FNTAFNTBPGGT1BCYP3A4RORC | |
| SCHEMBL6173339 | 0.89 | FNTA (0.55) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL3498572 | 0.87 | CYP3A4 (0.57) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6170815 | 0.86 | CYP3A4 (0.48) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL5737090 | 0.84 | FNTA (0.59) | FNTAFNTBPGGT1BCYP3A4RORC | |
| SCHEMBL6172263 | 0.82 | FNTA (0.54) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6171352 | 0.80 | FNTA (0.45) | FNTAFNTBPGGT1BCYP3A4RORC | |
| SCHEMBL5071351 | 0.80 | FNTA (0.64) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL3499579 | 0.80 | FNTA (0.67) | FNTAFNTBPGGT1BCYP3A4RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150973-B1 | HETEROARYL-SUBSTITUTED QUINOLIN-2-ONE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PROD INC (US) | 2005-06-15 | — | — | EP | claimed |