⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2041196 | 0.57 | — | — | |
| SCHEMBL3655474 | 0.57 | — | — | |
| SCHEMBL3937451 | 0.57 | — | — | |
| SCHEMBL7009257 | 0.54 | — | — | |
| SCHEMBL11532570 | 0.48 | — | — | |
| SCHEMBL895221 | 0.40 | — | — | |
| SCHEMBL11277497 | 0.40 | — | — | |
| SCHEMBL1468768 | 0.40 | — | — | |
| SCHEMBL2791127 | 0.38 | — | — | |
| SCHEMBL8109982 | 0.38 | TSHR (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903448-A | Polymer material of azacyclo olefin coordinated metal monoatom, preparation method and application thereof | 江西师范大学 | 2024-04-19 | — | — | CN | claimed |
| US-11814364-B2 | Pyridine N-oxide derivatives useful as factor XIa inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-14 | — | — | US | claimed |
| EP-4232444-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2023-08-30 | — | — | EP | claimed |
| EP-3966203-B1 | A METHOD FOR FUNCTIONALIZATION OF AN AROMATIC AMINO ACID OR A NUCLEOBASE | CF PLUS CHEMICALS S R O (CZ) | 2023-04-19 | — | — | EP | claimed |
| US-20230091768-A1 | PYRIDINE N-OXIDE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS | JANSSEN RESEARCH & DEVELOPMENT, LLC | 2023-03-23 | — | — | US | claimed |
| US-20230083973-A1 | SUBSTITUTED CYCLOPROPYL-2,2'-BIPYRIMIDINYL COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2023-03-16 | — | — | US | claimed |
| CN-115385886-A | AcrB efflux pump inhibitor and preparation method and application thereof | 山东大学 | 2022-11-25 | — | — | CN | claimed |
| US-20220177514-A1 | A METHOD FOR FUNCTIONALIZATION OF AN AROMATIC AMINO ACID OR A NUCLEOBASE | CF Plus Chemicals s.r.o. (CZ) | 2022-06-09 | — | — | US | claimed |
| EP-4007578-A1 | SUBSTITUTED CYCLOPROPYL-2,2'-BIPYRIMIDINYL COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma, Inc. (US) | 2022-06-08 | — | — | EP | claimed |
| WO-2022083569-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-04-28 | — | — | WO | claimed |
| US-4570000-A | HISTAMINE HH-2 ANTAGONISTS; GASTROINTESTINAL DISORDERS | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1986-02-11 | — | — | US | claimed |
| EP-0060696-B1 | NITROGEN HETEROCYCLES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-15 | — | — | EP | claimed |
| EP-0166533-A1 | Quinolone inotropic agents | Pfizer Limited (GB) | 1986-01-02 | — | — | EP | claimed |
| EP-0009683-B1 | BASIC PHENYL ETHERS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE PREPARATION OF THESE ETHERS AND COMPOSITIONS | MERCK PATENT GmbH (DE) | 1983-08-10 | — | — | EP | claimed |
| EP-0018542-B1 | PHENOTHIAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | MERCK PATENT GmbH (DE) | 1983-03-02 | — | — | EP | claimed |
| EP-0060696-A1 | Nitrogen heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| US-4289768-A | HYPOTENSIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-09-15 | — | — | US | claimed |
| US-4241168-A | TWO-EQUIVALENT MAGENTA COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1980-12-23 | — | — | US | claimed |
| EP-0018542-A1 | Phenothiazine derivatives, pharmaceutical compositions containing them and process for their preparation | MERCK PATENT GmbH (DE) | 1980-11-12 | — | — | EP | claimed |
| EP-0009683-A1 | Basic phenyl ethers, pharmaceutical compositions containing them and the preparation of these ethers and compositions | MERCK PATENT GmbH (DE) | 1980-04-16 | — | — | EP | claimed |