Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.46 |
| ▸ | CCKBR | P32239 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | XIAP | P98170 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179478 | 0.93 | CCKBR (0.44) | SCN9ACCKBR | |
| SCHEMBL6178218 | 0.88 | ACE (0.49) | SCN9ACCKBRCYP3A4XIAP | |
| SCHEMBL6177528 | 0.86 | SCN9A (0.42) | SCN9ACCKBR | |
| SCHEMBL6176827 | 0.85 | SCN9A (0.43) | SCN9ACCKBRCYP3A4XIAP | |
| SCHEMBL7423984 | 0.84 | SCN9A (0.50) | SCN9ACCKBRNPY1R | |
| SCHEMBL6177575 | 0.83 | ACE (0.43) | SCN9ACCKBR | |
| SCHEMBL6175287 | 0.83 | SCN9A (0.43) | SCN9ACCKBR | |
| SCHEMBL8521032 | 0.83 | CCKBR (0.45) | SCN9ACCKBRNPY1R | |
| SCHEMBL5712987 | 0.83 | CCKBR (0.45) | SCN9ACCKBRNPY1R | |
| SCHEMBL6178776 | 0.82 | SCN9A (0.41) | SCN9ACYP3A4XIAPNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |