Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 5/20 | 0.36 |
| ▸ | MMP9 | P14780 | 5/20 | 0.36 |
| ▸ | MMP1 | P03956 | 4/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175657 | 0.86 | IGF1R (0.45) | ITGALARPOLBL3MBTL1IGF1R | |
| SCHEMBL6176754 | 0.86 | ITGAL (0.44) | ITGALARPOLBL3MBTL1MMP2 | |
| SCHEMBL6173435 | 0.86 | IGF1R (0.45) | ITGALARPOLBL3MBTL1IGF1R | |
| SCHEMBL6171047 | 0.85 | IGF1R (0.48) | ITGALARPOLBL3MBTL1IGF1R | |
| SCHEMBL6172079 | 0.85 | IGF1R (0.47) | ITGALARPOLBL3MBTL1IGF1R | |
| SCHEMBL6175755 | 0.84 | ITGAL (0.38) | ITGALARPOLBL3MBTL1MMP2 | |
| SCHEMBL6175004 | 0.84 | IGF1R (0.42) | ITGALARIGF1RCYP3A4CYP2C9 | |
| SCHEMBL6177034 | 0.84 | IGF1R (0.40) | ITGALARPOLBL3MBTL1IGF1R | |
| SCHEMBL6174845 | 0.83 | NTRK1 (0.38) | ITGALARPOLBL3MBTL1MMP2 | |
| SCHEMBL6171611 | 0.83 | IGF1R (0.38) | ITGALARPOLBL3MBTL1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |