Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 17/20 | 1.00 |
| ▸ | CYSLTR1 | Q9Y271 | 17/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175619 | 1.00 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL27613239 | 0.82 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL2399856 | 0.82 | KDM4E (0.71) | CYSLTR2CYSLTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL2399852 | 0.82 | KDM4E (0.71) | CYSLTR2CYSLTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6176975 | 0.82 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL6177481 | 0.82 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL12894580 | 0.81 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10136232 | 0.81 | CYSLTR2 (0.77) | CYSLTR2CYSLTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6970201 | 0.81 | CYSLTR1 (1.00) | CYSLTR2CYSLTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6970207 | 0.81 | CYSLTR1 (1.00) | CYSLTR2CYSLTR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834510-B1 | Flavone derivative and medicine comprising the same | KOWA CO (JP) | 2005-02-23 | — | — | EP | disclosed |
| EP-0902007-B1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2003-11-05 | — | — | EP | disclosed |
| US-6136848-A | ANTIALLERGENS; ASTHMA THERAPY | KOWA CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0902007-A1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |
| EP-0834510-A2 | Flavone derivative and medicine comprising the same | KOWA CO. LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |