Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 17/20 | 1.00 |
| ▸ | CYSLTR2 | Q9NS75 | 16/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970201 | 1.00 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2KDM4ENPC1LMNA | |
| SCHEMBL6964077 | 0.93 | CYSLTR2 (1.00) | CYSLTR1CYSLTR2 | |
| SCHEMBL6964075 | 0.93 | CYSLTR2 (1.00) | CYSLTR1CYSLTR2 | |
| SCHEMBL6957585 | 0.85 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2 | |
| SCHEMBL6957581 | 0.85 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2 | |
| SCHEMBL6963471 | 0.83 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2MEN1ALDH1A1MAPT | |
| SCHEMBL6963468 | 0.83 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2MEN1ALDH1A1MAPT | |
| SCHEMBL6964172 | 0.83 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2KDM4EMEN1KMT2A | |
| SCHEMBL6969950 | 0.83 | CYSLTR2 (1.00) | CYSLTR1CYSLTR2 | |
| SCHEMBL6964179 | 0.83 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902007-B1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2003-11-05 | — | — | EP | disclosed |
| EP-0902007-A1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |