Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 8/20 | 0.37 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176578 | 0.92 | CCKBR (0.43) | CCKBRALDH1A1 | |
| SCHEMBL6178425 | 0.84 | CCKBR (0.44) | CCKBR | |
| SCHEMBL542390 | 0.81 | CCKBR (0.49) | CCKBRCCKAR | |
| SCHEMBL542264 | 0.80 | CCKBR (0.48) | CCKBRCCKAR | |
| SCHEMBL6176527 | 0.80 | CCKBR (0.49) | CCKBRCCKAR | |
| SCHEMBL6176540 | 0.79 | CCKBR (0.46) | CCKBRCCKAR | |
| SCHEMBL6175436 | 0.79 | CYP3A4 (0.36) | CCKBRALDH1A1KMT2A | |
| SCHEMBL6179105 | 0.78 | CCKBR (0.43) | CCKBRCCKAR | |
| SCHEMBL6179065 | 0.77 | CCKBR (0.43) | CCKBRCCKAR | |
| SCHEMBL6179067 | 0.77 | CCKBR (0.43) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |