SCHEMBL6176641

SCHEMBL6176641

Cc1noc(C)c1S(=O)(=O)Nc1cc(-c2ncc(C(F)(F)F)cc2Cl)ccc1Cl

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 7/20 0.46
ACLY P53396 1/20 0.46
ALDH1A1 P00352 3/20 0.44
POLB P06746 3/20 0.44
KDM4E B2RXH2 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
HTT P42858 2/20 0.41
BRD4 O60885 1/20 0.41
BRD2 P25440 1/20 0.41
BRD3 Q15059 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6174998 0.80 ALDH1A1 (0.54) MCL1ALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL6178807 0.79 MEN1 (0.53) MCL1ALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL6177491 0.74 ALDH1A1 (0.48) ALDH1A1POLBKDM4ESMN1; SMN2KMT2A
SCHEMBL6177219 0.72 ALDH1A1 (0.57) ALDH1A1POLBKDM4ESMN1; SMN2KMT2A
SCHEMBL8010576 0.72 ALDH1A1 (0.57) ALDH1A1POLBKDM4ESMN1; SMN2KMT2A
SCHEMBL6177104 0.69 MCL1 (0.45) MCL1ALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL27501382 0.69 SMN1; SMN2 (0.50) ALDH1A1POLBKDM4ESMN1; SMN2KMT2A
SCHEMBL6176079 0.68 ALDH1A1 (0.52) ALDH1A1POLBKDM4ESMN1; SMN2KMT2A
SCHEMBL6175116 0.68 ALDH1A1 (0.55) ALDH1A1POLBKDM4ESMN1; SMN2KMT2A
SCHEMBL6177660 0.67 ALDH1A1 (0.46) ALDH1A1POLBKDM4ESMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708756-B1 SUBSTITUTED 2-PHENYLPYRIDINES WITH HERBICIDAL ACTION BASF AG (DE) 2005-06-01 EP disclosed
US-5783522-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-07-21 US disclosed
CN-1127504-A Substituted 2-phenylpyridines with herbicidal action BASF AG (DE) 1996-07-24 CN disclosed
EP-0708756-A1 SUBSTITUTED 2-PHENYLPYRIDINES WITH HERBICIDAL ACTION BASF AKTIENGESELLSCHAFT (DE) 1996-05-01 EP disclosed
WO-1995002580-A2 SUBSTITUTED 2-PHENYLPYRIDINES WITH HERBICIDAL ACTION BASF AKTIENGESELLSCHAFT (DE) 1995-01-26 WO disclosed