Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178791 | 0.77 | TSHR (0.43) | TSHRTDP1ALDH1A1 | |
| SCHEMBL13811806 | 0.75 | TSHR (0.35) | TSHRTDP1ALDH1A1 | |
| SCHEMBL4945284 | 0.71 | MAPK1 (0.36) | TSHRTDP1ALDH1A1 | |
| SCHEMBL3837144 | 0.71 | TSHR (0.32) | TSHRTDP1ALDH1A1 | |
| SCHEMBL18408740 | 0.71 | TSHR (0.32) | TSHRTDP1ALDH1A1 | |
| SCHEMBL7961121 | 0.71 | LMNA (0.32) | TSHRTDP1ALDH1A1 | |
| SCHEMBL3308090 | 0.71 | TSHR (0.32) | TSHRTDP1ALDH1A1 | |
| SCHEMBL1142694 | 0.69 | — | — | |
| SCHEMBL9036085 | 0.69 | — | — | |
| SCHEMBL6177562 | 0.67 | TSHR (0.31) | TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |