Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 8/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415118 | 0.96 | F2 (0.58) | F2ITGA4ESR1ESR2 | |
| Oxalic Acid SCHEMBL7418562 | 0.92 | F2 (0.52) | F2ITGA4ESR1ESR2 | |
| Oxalic Acid SCHEMBL6605838 | 0.90 | F2 (0.48) | F2ITGA4ESR1ESR2 | |
| Oxalic Acid SCHEMBL6605436 | 0.89 | F2 (0.48) | F2ITGA4ESR1ESR2 | |
| Oxalic Acid SCHEMBL7986025 | 0.89 | F2 (0.62) | F2ITGA4ESR1ESR2HTT | |
| SCHEMBL6606510 | 0.89 | F2 (0.50) | F2ITGA4ESR1ESR2 | |
| SCHEMBL6611328 | 0.88 | F2 (0.49) | F2ITGA4ESR1ESR2 | |
| Lithium SCHEMBL6611346 | 0.88 | F2 (0.49) | F2ITGA4ESR1ESR2 | |
| Oxalic Acid SCHEMBL7990629 | 0.87 | F2 (0.60) | F2ITGA4ESR1ESR2HTT | |
| Oxalic Acid SCHEMBL7414182 | 0.87 | F2 (0.51) | F2ITGA4ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-01-05 | — | — | EP | disclosed |
| US-6391901-B1 | Thrombin inhibitors | ELI LILLY AND COMPANY | 2002-05-21 | — | — | US | disclosed |