Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.62 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 7/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7990629 | 0.96 | F2 (0.60) | F2ITGA4ESR1ESR2HTT | |
| SCHEMBL6597629 | 0.95 | F2 (0.67) | F2ITGA4ESR1ESR2LTA4H | |
| SCHEMBL7982501 | 0.95 | F2 (0.67) | F2ITGA4ESR1ESR2LTA4H | |
| Oxalic Acid SCHEMBL7986090 | 0.95 | ITGA4 (0.60) | F2ITGA4ESR1ESR2 | |
| SCHEMBL6596926 | 0.91 | ITGA4 (0.69) | F2ITGA4ESR1ESR2LTA4H | |
| SCHEMBL7415846 | 0.91 | F2 (0.62) | F2ITGA4ESR1ESR2LTA4H | |
| SCHEMBL7981973 | 0.91 | F2 (0.64) | F2ITGA4ESR1ESR2LTA4H | |
| SCHEMBL6596335 | 0.90 | ITGA4 (0.68) | F2ITGA4ESR1ESR2LTA4H | |
| Oxalic Acid SCHEMBL6173739 | 0.90 | F2 (0.57) | F2ITGA4ESR1ESR2HTT | |
| Oxalic Acid SCHEMBL6174272 | 0.90 | F2 (0.57) | F2ITGA4ESR1ESR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284756-B1 | ANTICOAGULANT | ELI LILLY AND COMPANY | 2001-09-04 | — | — | US | disclosed |