Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PTPRE | P23469 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178899 | 0.89 | MAOB (0.43) | MAOBALDH1A1MAPK1PIM1MAP2K2 | |
| SCHEMBL6179847 | 0.88 | MAOB (0.42) | MAOBALDH1A1MAPK1PIM1MAP2K2 | |
| SCHEMBL6176694 | 0.78 | MAOB (0.39) | MAOBALDH1A1PIM1MAP2K2CDK8 | |
| SCHEMBL6177204 | 0.76 | POLB (0.36) | MAOBALDH1A1POLBNPC1TDP1 | |
| SCHEMBL6178817 | 0.73 | CA12 (0.41) | ALDH1A1MAPTNPSR1TSHRMEN1 | |
| SCHEMBL7869588 | 0.72 | POLB (0.37) | ALDH1A1POLBNPC1TDP1L3MBTL1 | |
| SCHEMBL7866131 | 0.71 | NPC1 (0.40) | ALDH1A1MAPK1CDK8POLBNPC1 | |
| SCHEMBL7392946 | 0.68 | L3MBTL1 (0.43) | ALDH1A1CDK8NPC1L3MBTL1ATM | |
| SCHEMBL6176686 | 0.67 | SERPINE1 (0.63) | — | |
| SCHEMBL3747084 | 0.65 | NPC1 (0.38) | ALDH1A1NPC1TDP1L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092716-B1 | Derivatives of benzothiophenes, benzofurans and indoles, method for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-02-16 | — | — | EP | disclosed |
| US-6302837-B1 | ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 2001-10-16 | — | — | US | disclosed |
| EP-1092716-A2 | Derivatives of benzothiophenes, benzofurans and indoles, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-04-18 | — | — | EP | disclosed |